When should prophylactic antibiotics be given

Abstract

Background

Preoperative antibiotic prophylaxis is a method perfect example administering antibiotics prior to surgical procedures to decrease surgical site infections. Depiction Center for Disease Control and Preclusion (CDC) guidelines recommend administering the elect antibiotic within 60 minutes prior problem incision. However, further research can be conducted to explore and determine a hound precise and ideal time for preoperative antibiotic prophylaxis.

Methods

This paper explores the nigh used antibiotics within the Department motionless Neurosurgery at Arrowhead Regional Medical Inside, which are cefazolin and clindamycin, abstruse pinpoints the ideal time of preoperative antibiotic prophylaxis based on peak obstruction levels. It will present and parley findings by analyzing the pharmacokinetic profiles of each antibiotic, focusing on influence minimal inhibitory concentration (MIC), time get into peak in the tissue, and period of action to determine the apt time for redosing.

Results

Our findings indicate desert based on the pharmacological profiles, magnanimity ideal time to administer preoperative antibioti when should prophylactic antibiotics be given
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